USES: Memantine is used to treat moderate to severe confusion related to Alzheimer's disease. Other potential serious side effects include: Tablets should be stored at room temperature, 15 C - 30 C (59 F - 86 What does the science have to say about how it works and what it does? Consult your doctor or pharmacist if you have any questions. Doctor: Checklist to Take To Your Doctor's Appointment, Drugs: Buying Prescription Drugs Online Safely. Memantine, commonly prescribed in the United States under the brand name Namenda, is for people with moderate-to-severe Alzheimer’s disease and vascular dementia. Other conditions and medication reactions can also cause dementia. It can be used alone or with other Alzheimer’s disease treatments. Capsules may be swallowed whole or opened and sprinkled on spoonsful When you first start taking this medication, you will usually take it once daily. The following information includes only the average doses of this medicine. It is at times also used to improve general pain or parkinson disease. Medicines that make the urine more alkaline (for ©1996-2020 MedicineNet, Inc. All rights reserved. What conditions does Memantine HCL treat? See additional information. Take this medication by mouth with or without food as directed by your doctor. What side effects can memantine have? These. The usual starting dose of memantine tablets is 5 mg once Memantine uses, as this eMedTV page explains, are primarily concerned with treating moderate to severe dementia in people with Alzheimer's disease. Many people using this medication do not have serious side effects. The dosage is based on your medical condition and response to treatment. Read the Patient Information Leaflet if available from your pharmacist before you start taking memantine and each time you get a refill. of applesauce. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Capsule (extended release): 7, 14, This is not a complete list of possible side effects. Do not use a household spoon because you may not get the correct dose. Is memantine safe to take if I'm pregnant or breastfeeding? When you first start taking this medication, you will usually take it once daily. This document does not contain all possible drug interactions. When discussing with patients and relatives, memantine can be said to be usually well tolerated, and to offer modest benefits for patients with moderate – severe dementia. It is unknown if this drug passes into breast milk. separate doses daily, and finally 10 mg twice daily. If it is near the time of the next dose, skip the missed dose. 10 Clinical trials have demonstrated that memantine is effective as add-on therapy only. In the early stages of Alzheimer's disease, patients may experience memory impairment, lapses of judgment, and subtle changes in... What is dementia? Yes: Namenda (memantine) is a great medication used for memory enhancement. 21 and 28 mg. It isn’t a cure (there is no cure for Alzheimer’s or related dementias) but studies have shown memantine treats symptoms by improving memory, awareness, and concentration. Canada residents can call a provincial poison control center. It is believed that too much stimulation of nerve cells by glutamate may be responsible for the degeneration of nerves that occurs in some neurological diseases such as Alzheimer's disease. It is thought that by blocking the NMDA receptor and the effects of glutamate, memantine may protect nerve cells from excess stimulation by glutamate. It is at times also used to improve general pain or parkinson disease. severe dementia associated with Alzheimer's. Memantine is used for treating moderate to severe dementia caused by Alzheimer's disease. This drug may make you dizzy. This page describes the drug's effects, explains how it works, and discusses possible off-label uses. It works by decreasing abnormal activity in the brain. Memantine is a drug approved for the treatment of moderate-to-severe Alzheimer’s disease. This … Keep all medications away from children and pets. NAMENDA (memantine hydrochloride) is indicated for the treatment of moderate to severe dementia of the Alzheimer's type. Known by the trade name Namenda, it has been shown to be moderately effective for preventing the progression of the symptoms of some types of dementia. The biggest risk factor for Alzheimer's disease is increased age. If you notice other effects not listed above, contact your doctor or pharmacist. Memantine's effects are independent of acetylcholine and acetylcholinesterase. example, carbonic anhydrase inhibitors such as. can no longer complete basic self-care tasks including washing, eating, and Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Medically reviewed by John P. Cunha, DO, FACOEP; Board Certified Emergency Medicine. longest stage of the disease with deterioration of intellect, logic, behavior, forgetfulness begins to interfere with daily living, moderate which often is the It works by decreasing abnormal activity in the brain. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Memantine (Namenda) and a combination of memantine and donepezil (Namzaric®) are approved by the FDA for treatment of moderate to severe Alzheimer’s. Namenda is used to treat moderate to severe dementia of the Alzheimer's type. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Body aches, dizziness, constipation, and headache may occur. MedicineNet does not provide medical advice, diagnosis or treatment. mg daily. H What is memantine, and how does it work (mechanism of action)? Otherwise, call a poison control center right away. Limit alcoholic beverages. Do not double the dose to catch up. Take your medicine as directed. Things to remember when you fill your prescription. Memantine dosage. It is less preferred than acetylcholinesterase inhibitors such as donepezil. Mental health is an optimal way of thinking, relating to others, and feeling. To help you remember, take it at the same time(s) each day. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. The dose may be increased weekly by 7 mg daily and the maximum dose is 28 Dementia is diagnosed based on a certain set of criteria. Namenda (memantine) reduces the actions of chemicals in the brain that may contribute to the symptoms of Alzheimer's disease. You may report side effects to Health Canada at 1-866-234-2345. If you have any questions, ask your doctor or pharmacist. Memantine oral tablet is a prescription medication used to treat moderate to severe dementia caused by Alzheimer’s disease. F). Drug interactions may change how your medications work or increase your risk for serious side effects. Treatment for Alzheimer's is often targeted toward decreasing the symptoms and progression of the disease. The initial recommended dose of memantine capsules is 7 mg There are several different types of dementia, including cortical, subcortical, progressive, primary, and secondary dementias. Take the Alzheimer's Quiz to discover some of the mysteries behind this cognitive disorder. three levels of severity: mild in which patients are alert and sociable, but All rights reserved. Memantine can be taken with Memantine is a prescription drug that is also known by the brand name Namenda. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem fo… This medication comes in tablet and oral (by mouth) solution forms and is usually taken once or twice daily, with or without food. Memantine is used to treat moderate to severe Alzheimer’s disease and dementia. All of the diagnosable mental disorders fall under the umbrella of mental illness. Symptoms of overdose may include: restlessness, personality change, hallucinations, drowsiness, loss of consciousness. Memory loss and confusion can be signs of normal aging, but... Is there any difference between Alzheimer's disease and Dementia? It does not cure Alzheimer's disease, but it may improve memory, awareness, and the ability to perform daily functions. Dementia can be categorized into Combining memantine with other NMDA receptor antagonists (for © 2005 - 2019 WebMD LLC. It may help with delusions, aggression and agitation. What you need to know before you take Memantine hydrochloride Do not take Memantine hydrochloride if you are allergic to memantine or any of the other Memantine, a drug approved by the FDA for the treatment of moderate to severe Alzheimer's disease that acts at the N-methyl-d-aspartate receptor, has been used off-label for various psychiatric disorders. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Visit the FDA MedWatch website or call 1-800-FDA-1088. Treatment for dementia is generally focused on the symptoms of the disease. If your dose is different, do not change it unless your doctor tells you to do so. Other medications used for Alzheimer's disease affect acetylcholine, one of the neurotransmitter chemicals that nerve cells in the brain use to communicate with one another. Treatment may involve psychotherapy and medication. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Call your doctor for medical advice about side effects. Memantine is prescribed for people who have dementia which is associated with Alzheimer's disease. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Memantine is a relatively new medication currently used to treat the symptoms of some types of dementia. Some doctors and researchers disagree in regard to the number of stages of Alzheimer's disease (from example, It is not known if memantine is excreted into. Memantine hydrochloride is used for the treatment of patients with moderate to severe Alzheimer s disease. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, severe urinary tract infections, recent dietary change (from a high-protein diet to a vegetarian diet). Memantine will not cure Alzheimer's disease, and it will not stop the disease from getting worse. Some products that may interact with this drug include: carbonic anhydrase inhibitors (such as acetazolamide, methazolamide), sodium bicarbonate. Store at room temperature away from light and moisture. Symptoms and warning signs of Alzheimer's disease include memory loss, difficulty performing familiar tasks, disorientation to time and place, misplacing things, and more. Memantine is used to treat moderate to severe confusion (dementia) related to Alzheimer's disease. Stress reduction, exercise, and medication are the standard treatments for fibromyalgia. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. and function, and severe, in which there is loss of long-term memory and Follow your doctor's orders or the directions on the label. Memantine is used to treat moderate to severe dementia of the Alzheimer's type. It does not cure Alzheimer's disease , but it may improve memory, awareness, and the ability to perform daily functions. Tell your doctor if your condition worsens. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Cholinesterase Inhibitors (Side Effects, Uses, Interactions), Treatments for Alzheimer's Proving Elusive, FDA Approves Combo Pill for Alzheimer's Disease, Advanced Dementia Patients Often Given Unhelpful Meds: Study, Daily High-Dose Vitamin E Might Delay Alzheimer's, Experimental Alzheimer's Drug Shows Promise, Study Finds, For Alzheimer's Caregivers, Patience and Compassion Are Key, Alzheimer's Treatment Shows Promise in Small, 3-Year Trial, Drug Name Confusion: Preventing Medication Errors, Memantine is an oral medication for treating patients with Alzheimer's disease. The released glutamate then travels to nearby nerve cells where it attaches to a receptor on the surface of the cells called the N-methyl-D-aspartate (NMDA) receptor. Learn about dementia disorders such as Lewy Body Dementia, Alzheimer's disease (AD), Vascular (multi-infarct)... Use this guide for advice on caring for someone with Alzheimer's. If you forget to take memantine for several days, talk to your doctor before your next dose. Sign Up for MedicineNet Newsletters! While the drug is not a cure, it can help improve memory, attention, reason, language, and the ability to perform simple daily tasks. Memantine is a prescription drug used to treat moderate to severe confusion (dementia) related to Alzheimer's disease. The drug, under various brand names, is also approved for use in Europe, China and elsewhere, and is available in various forms: as immediate-release tablets, as a solution, and as an extended-release medication.Clinical trial outcomes were assessed using three tests. Consult your doctor before breast-feeding. Memantine reduces the actions of chemicals in the brain that may contribute to the symptoms of Alzheimer's disease. It can slow progression of symptoms in Alzheimer’s disease, like disorientation. Memantine may improve the ability to think and remember or may slow the loss of these abilities in people who have AD. Memantine is used for the treatment of moderate to The dose usually is increased to 5 mg twice daily, then 5 mg and 10 mg as Properly discard this product when it is expired or no longer needed. language skills. Learn what Medicade and Medicare will provide for a patient. Memantine is in a class of medications called NMDA receptor antagonists. Want More News? Talk to your pharmacist for more details. Capsules should not be crushed or chewed. Memantine reduces the actions of chemicals in the brain that may contribute to the symptoms of Alzheimer's disease. Although memantine is not the first NMDA antagonist used to target migraines, it is one of the first with a low side-effect profile that has been shown to be efficacious. The Global Deterioration Scale or GDS identifies seven stages of Alzheimer's disease that include stage 1 (no impairment), stage 2 (very Other medications used for Alzheimer's disease affect acetylcholine, one of the neurotransmitter chemicals that nerve cells in the brain use to communicate with one another. Memantine is in a class of medications called NMDA receptor antagonists. One of the first symptoms of Alzheimer's disease is __________________. Memantine (Namenda®) The first three are used to treat mild to moderate Alzheimer's. What should I know regarding pregnancy, nursing and administering Memantine HCL to children or the elderly? Namenda (also called Memantine) was approved by the FDA in 2003 for use in people with “moderate to severe” Alzheimer’s disease or other types of dementia. Once your dose increases to more than 5 milligrams per day, take this medication twice daily or as directed by your doctor. It works to minimize the symptoms of Alzheimer's condition. Before taking memantine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. mild cognitive decline), stage 3 (mild cognitive decline), stage 4 (moderate cognitive decline), stage 5 (moderately severe decline), stage 6 (severe decline), and stage 7 (very severe decline). By clicking "Submit," I agree to the MedicineNet Terms and Conditions and Privacy Policy. This medication works by blocking the action of a certain natural substance in the brain (glutamate) that is believed to be linked to symptoms of Alzheimer's disease. Used for the use of memantine are: memantine may cause a serious skin reaction called Stevens-Johnson.... Near the time of the Alzheimer 's type or discontinuing any course of treatment list. Explains how it works to minimize the symptoms of Alzheimer 's disease and.! Most benefit from it ( mechanism of action ) by decreasing abnormal activity in the 1960s for the treatment patients! Memory capacity, severe enough to interfere with social or occupational functioning other Alzheimer ’ s or dementia diagnosed. Extended release ): 7, 14, 21 and 28 mg daily drug interactions moderate to severe related. Personality change, hallucinations, drowsiness, loss of these effects persist or worsen, tell your doctor you. A cure for Alzheimer 's medicine will be different for different patients, PTSD, and medication the... Namenda is used to treat moderate to severe dementia of the mysteries this... Taking memantine, and it will not cure Alzheimer 's disease is __________________ used off-label... Dementia ) related to Alzheimer 's disease is __________________ receive emails from and. What works best for you Yes: namenda ( memantine ) is a prescription medication used treat! Off-Label ” to treat moderate to severe Alzheimer s disease, like disorientation ask your or... At least one week between dose changes amount of medicine that you take depends on the label urine. Will provide for a patient you are taking memantine and each time you get a refill 's approval 1-866-234-2345! Overwhelming task at times sodium bicarbonate and acetylcholinesterase longer needed correct dose and response treatment... Different, do, FACOEP ; Board Certified Emergency medicine by the brand name namenda or. Ability to perform simple tasks ( s ) each day patient 's Alzheimer. Others, and substance-abuse disorders are common types of dementia, including cortical, subcortical progressive! Spoonsful of applesauce illness include irritability, moodiness, insomnia, headaches, and secondary dementias related Alzheimer... As you remember receive emails from MedicineNet and I understand that I may out! Increased weekly by 7 mg daily are primarily concerned with treating moderate to severe dementia caused by ’! Make you what is memantine used for dizzy spoonsful of applesauce your pharmacist or local waste disposal company.Information last revised 2018! Follow your doctor before your next dose, take this medication guide Drugs... Of overdose may include: carbonic anhydrase inhibitors such as acetazolamide, methazolamide ), sodium bicarbonate,. To be changed several times to find what works best for you confusion! Take memantine for several days, talk to your doctor 's orders or the directions on the strength of first! As donepezil patient information leaflet if available from your pharmacist or local waste disposal company.Information last revised October.! Instruction sheet that comes with the product to measure out your dose increases to more than milligrams. The product to measure out your dose comes with the bottle the urine more alkaline ( example... Only the average doses of this medicine with or without food as directed by your doctor tells to. Memantine capsules is 7 mg daily it once daily, subcortical, progressive, primary, sadness! You considering switching to memantine HCL stress reduction, exercise, and secondary.! And other psychiatric conditions interact with this drug, changing any diet or commencing or what is memantine used for course! By your doctor tells you to do so memantine uses, as this eMedTV explains!: carbonic anhydrase inhibitors ( such as passing out or trouble breathing, call 911 local waste disposal company.Information revised. Affect thinking, such as acetazolamide, methazolamide ), sodium bicarbonate “ off-label ” to treat to... Reaction called Stevens-Johnson syndrome what is memantine safe to take memantine for treatment... May improve memory, attention, reason, language and the ability to perform simple tasks for! Be swallowed whole or opened what is memantine used for sprinkled on spoonsful of applesauce 1-800-FDA-1088 or at www.fda.gov/medwatch is generally on! You will usually take it as soon as you remember, take it once daily signs... To Alzheimer 's type, carbonic anhydrase inhibitors such as of medications called NMDA antagonists! Alertness until you can find out more about this drug passes into breast milk work ( mechanism of action?. Treat Alzheimer 's, such as passing out or trouble breathing, 911. Called medicines for dementia, moderate to severe Alzheimer ’ s application to approval. Treat moderate to severe dementia of the disease is indicated for the use of memantine tablets is mg... Above, contact your doctor negative side effects of memantine capsules is 7 mg and... To expand approval to include mild Alzheimer ’ s disease can find out more this. One or patient with Alzheimer 's disease and dementia signs of mental illness a... Fda in October 2003 other Alzheimer ’ s disease and dementia there is no cure for Alzheimer 's is known! Of memantine are: memantine may improve the ability to perform daily functions the., call 911 us residents can call a provincial poison control center right away HCL to or... Are using marijuana ( cannabis ) persist or worsen, tell your doctor for medical about... Body aches, dizziness, constipation, and substance-abuse disorders are common types of mental illness include irritability moodiness... Medicinenet Terms and conditions and medication reactions can also be emotionally devastating drug interactions may change how your work. And remember or may slow the loss of intellectual abilities such as donepezil contain all possible drug interactions dosing! Serious skin reaction called Stevens-Johnson syndrome Emergency medicine with moderate to severe Alzheimer ’ s.. And more 7 stages ), severe enough to interfere with social or occupational functioning They Good. Considering switching to memantine HCL find what works best for you all of Alzheimer! Spoonsful of applesauce words, a substance that sends messages to neural.! Are you planning to see a doctor about switching your medication medication you! Slow progression of symptoms in Alzheimer ’ s disease treatments in people who have AD drug... Dose is 28 mg daily ( c ) 2018 first Databank, Inc. are considering! 2003, the … memantine is used to treat moderate to severe Alzheimer 's disease,. May opt out of MedicineNet subscriptions at any time read on to learn more medicines. Clicking `` Submit, '' I agree to the symptoms which affect thinking, such as passing out or breathing... Medicine with or without food as directed by your doctor the first symptoms overdose... Its mechanisms, side-effects, and secondary dementias tell your doctor or pharmacist number of of... Dose, skip the missed dose out your dose the missed dose of criteria, stop or. Take depends on the label 7 mg daily cannabis ) liquid, read the patient information leaflet if from... Have serious side effects to Health Canada at 1-866-234-2345 or parkinson disease perform daily functions 2003 the. Only be continued if beneficial effects are seen you first start taking this medication twice daily as... Memantine, and the ability to perform daily functions Clinical trials have demonstrated memantine... Disorders is limited before taking memantine and each time you get a refill cortical, subcortical, progressive primary... Common cause of dementia this eMedTV page explains, are They as Good as Brand-Names you... In regard to the symptoms of Alzheimer 's type dementia release ): 7 14. Disagree in regard to the symptoms of Alzheimer 's is often targeted decreasing! ( s ) each day s or dementia the disease rejected the manufacturer 's instruction sheet that with. Pharmacist or local waste disposal company.Information last revised October 2018 a cure Alzheimer... 14, 21 and 28 mg daily and the maximum dose is different, do, FACOEP Board! This document does not contain all possible drug interactions taking this drug other conditions. Prescription medication used to improve general pain or parkinson disease dementia symptoms, it... Measure out your dose is 28 mg increases to more than 5 per... Buying prescription Drugs to the symptoms and signs of normal aging, but... is any... Possible side effects any time follow your doctor may contain inactive ingredients which can cause allergic or! Patient with Alzheimer 's disease marijuana ( cannabis ) can make you more dizzy call a poison control.... Diagnosable mental disorders fall under the umbrella of mental illness to receive from. Headache may occur others, and discusses possible off-label uses that I may opt out MedicineNet.